Predictive factors of intrauterine insemination success of women with infertility over 10 years.
نویسندگان
چکیده
OBJECTIVE The relationship between maternal age, duration of infertility, pre-ovulatory follicles, endometrial thickness and motile sperms with intra uterine insemination (IUI) success in women with infertility over 10 years was surveyed. METHODS We performed a descriptive - cross sectional study among couples (n=26) with a history of infertility for more than 10 years who were treated with IUI. The data was collected between 2000 and 2007 in the fertility ward of Amiralmomenin Hospital of Semnan University of Medical Sciences. Patients underwent a basic fertility workup and the ovarian hyperstimulation was done with clomiphene citrate (CC) and human chorionic gonadotrophin (hMG) alone or in combination. A volume of 0.3-0.4 ml suspension of processed spermatozoa (after swim-up procedure) was introduced into the uterine cavity 36h after human chorionic gonadotrophin (hCG) administration. The comparison between variables was performed by chi-square and student's test on SPSS (Version 10.0). RESULTS The total number of women with infertility over 10 years referring to fertility ward was 26. Seven of them became pregnant after treatment (27%). Majority of these pregnancies (87.5%) were achieved in the first cycle. Pregnant cases were 30-37 years of age with a history of infertility for up to ten years. The comparison of data between two groups showed that maternal age (P<0.03) and number of motile sperms (P<0.05) had a significant relationship with the results of treatment. CONCLUSION Number of motile spermatozoa and women age are factors with the highest impact on pregnancy after IUI treatment in women with infertility for over 10 years.
منابع مشابه
P-148: Predictive Factors for Pregnancy after Intrauterine Insemination: A Retrospective Study of Factors Affecting Outcome
Background: Controlled ovarian hyper stimulation (COH) in conjunction with intrauterine insemination (IUI) is frequently used to treat various causes of infertility in couples. In this study we evaluate the relation between IUI outcomes and infertility with the intent to detect the most important parameters that pertain to a successful IUI. Materials and Methods: In this cross-sectional study, ...
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متن کاملIntrauterine insemination treatment in subfertility: an analysis of factors affecting outcome.
A total of 811 intrauterine insemination (IUI) cycles in which clomiphene citrate/human menopausal gonadotrophin (HMG) was used for ovarian stimulation were analysed retrospectively to identify prognostic factors regarding treatment outcome. The overall pregnancy rate was 12.6% per cycle, the multiple pregnancy rate 13.7%, and the miscarriage rate 23.5%. Logistic regression analysis revealed fi...
متن کاملThe Role of Infertility Etiology in Success Rate of Intrauterine Insemination Cycles: An Evaluation of Predictive Factors for Pregnancy Rate
BACKGROUND The objective of this study was to identify the prognostic factors that influence the outcome of ovarian stimulation with intrauterine insemination (IUI) cycles in couples with different infertility etiology. MATERIALS AND METHODS This retrospective study was performed in data of 1348 IUI cycles with ovarian stimulation by clomiphene citrate (CC) and/or gonadotropins in 632 women w...
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عنوان ژورنال:
- JPMA. The Journal of the Pakistan Medical Association
دوره 61 2 شماره
صفحات -
تاریخ انتشار 2011